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Exam NCLEX-PN topic 4 question 54 discussion

Actual exam question from Test Prep's NCLEX-PN
Question #: 54
Topic #: 4
[All NCLEX-PN Questions]

Which of the following clients should refrain from therapy with the thiazide diuretic hydrochlorothiazide (HCTZ)?

  • A. a client with renal impairment
  • B. a client with hypertension
  • C. a client with diabetes mellitus, type II
  • D. a client with renal calculi (kidney stones)
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Suggested Answer: C 🗳️
The thiazide class of diuretics cause metabolic abnormalities such as elevated blood glucose levels. This elevation is caused in part by diuretic-induced potassium deficiency. Hypokalemia reduces the secretion of insulin by pancreatic beta cells, thereby increasing plasma glucose levels. Thiazides have been used for many years in clients with the conditions described in choices 1 and 2. Thiazides decrease calcium excretion, thus decreasing the likelihood of renal calculi.
Pharmacological Therapies

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