As the question talk about virtual disk, we should refer to VMDK.
Intra-VM VMDK Affinity Rule
Intra-VM VMDK Anti-Affinity Rule
And after the question refer to "Different Datastore" it let us with one option
Intra-VM VMDK Anti-Affinity Rule
This links shows it clearly
https://docs.vmware.com/en/VMware-vSphere/6.7/com.vmware.vsphere.resmgmt.doc/GUID-A55935B4-2B4E-48A4-9D53-BB13ABDD5A60.html
VM Anti-Affinity Rule
An anti-affinity rule places a group of virtual machines across different hosts, which prevents all virtual machines from failing at once in the event that a single host fails
Intra-VM VMDK Affinity Rule
By default Storage DRS applies an Intra-VM affinity rule to all new virtual machines in the datastore cluster. The Intra-VM affinity rule keeps the virtual machine files, such as VMX file, log files, vSwap and VMDK files together on one datastore
VM-Host Affinity Rule
You can create VM-Host affinity rules to specify whether or not the members of a selected virtual machine DRS group can run on the members of a specific host DRS group
Intra-VM VMDK Anti-Affinity Rule
You can create a VMDK anti-affinity rule for a virtual machine that indicates which of its virtual disks must be kept on different datastores. VMDK anti-affinity rules apply to the virtual machine for which the rule is defined, not to all virtual machines.
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